Team Target started first and second in last year's race at Sonoma.
Kanaan earned a spot on the podium with a third-place finish and Dixon finished right behind him in fourth.
CGR has all but mastered the art of racing at Mid-Ohio, earning six wins at the track in the last seven races.
Chip Ganassi Racing heads into Mid-Ohio, winning six of the last seven races at the course.
Kanaan has three podium finishes in the past three races and knows the importance of momentum.